Helpful Tools and Information:
- Policies and Guidelines
- Treatment (Tx) and Controlled Drugs
*For a detailed description of LARC Veterinary Services go to LARC staff tab on website and look under Staff responsibilities.
Pharmaceutical Grade Agents
NIH, USDA, and UCSF guidelines, regulations and policy require that compounds used in research animals be pharmaceutical-grade when available.
How to tell the compound is pharmaceutical-grade
The simplest approach is to look for the letters USP in the catalog or on the label. This means it is an FDA-labeled human or veterinary medication or sterile fluid, made to FDA’s approved standards. If it does not say “USP” but you think it may still meet NIH-OLAW’s standards [insert link] contact IACUC or LARC for advice.
Non-medicines such as cells, toxins, fixatives and not-yet-licensed medicines are not available as pharmaceutical-grade USP agents. Sterile saline, sterile water-for-injection and phosphate-buffered saline (PBS) are available as USP pharmaceuticals.
Obtaining pharmaceutical-grade USP agents for animal studies:
Many pharmaceutical agents are only available by prescription from a licensed health professional (MD, veterinarian, dentist) and cannot be ordered directly in your lab.
- Controlled Substances (such as ketamine, barbiturates, buprenorphine): work with your OEH&S Departmental Safety Advisor (DSA) to set up your Controlled Substances Authorization (CSA) and purchasing, storage, and records-keeping practices. Click here for EHS CSA program. LARC does not order controlled substances for research laboratories
- Human medications: Go to www.cardinalhealth.com or contact the UCSF Pharmacy, Vicky Pung or Tony Davoren and submit the account set-up form (click here for form) in your initial email. They will ask specifics for your area and cost center information to set up an account that will allow you to order non-controlled human drugs (e.g., cancer chemotherapeutics, sterile fluids, through their arrangement with Cardinal Health, for pickup at the UCSF Inpatient Pharmacy at Mount Zion, Parnassus or Mission Bay. The study must be a UCSF study and in a UCSF lab/clinic. Offsite labs or clinics will not be eligible. E.G., if your study is being conducted at SFGH, you would not be able purchase from UCSF Pharmacy. The purchases will be recharged to your cost center on a monthly basis.
- Veterinary Medications: LARC orders veterinary prescription medicines on a fee-for-service basis. Common veterinary agents available include isoflurane, antibiotics, xylazine, bupivacaine, meloxicam and carprofen. For inquiries or to place an order, send an email to LARCsupplyrequest@ucsf.edu. If a new customer, include PI name, LARC Investigator Billing Code, and detailed information on what you need to purchase.
All agents purchased must be listed in the correct section of Section I of your RIO animal use authorization.